Cytotoxicity of gold nanorods and nanoribbons in context of biomedical applicationsPart of:
In recent years variety of metallic nanostructures have been proposed as components of systems for cancer diagnostic and therapy. Especially gold and silver nanoparticles of different shapes, sizes and properties are widely investigated for biomedical applications such as contrast agents in diagnostics, matrices in drug delivery, vectors for gene therapy or even components of antiseptic systems.
The main goal of this study is to compare the cytotoxic effect of different shapes of gold nanoparticles (GNP) prepared by the use of selected dimeric surfactants, namely nanorods and nanoribbons on cancer (LNCaP) and normal (PNT1A) prostate cell lines. In order to investigate the cytotoxicity of GNPs, MTT test and flow cytometry were performed.