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Poster

Enhancing the functionalities of bioactive glass-based scaffolds by novel polymeric coatings

Part of:
Line-Up:
- Plenary Lecture Test Ploetz 1 Alexia Ploetz
- Poster Investigating Dynamic Biological Processes with High-Speed, High-Resolution Correlative AFM-Light Microscopy 1 Oilibhe Pabsch
- Poster Corrosion behaviour of potencially biodegradable ternary alloy Zn-Mg-Ca 1 Dipl.-Ing. Jan Pinc
- Poster Multi scale topography in titanium alloys by electron beam technique: influence on the tissue adhesion and bacterial contamination 1 Dr. Fernando Warchomicka
- Poster Cytotoxicity of gold nanorods and nanoribbons in context of biomedical applications 1 Marika Musielak
- Poster Preliminary studies of synthesis of gold nanoribbons using selected dicationic surfactants 1 Joanna Patalas
- Poster Diclofenac release from a silicon based hydrogel for contact lenses controlled by a layer-by-layer coating 1 Prof. Ana Serro
- Poster Synthesis, solubility and optical activity of chiral poly(2,4-disubstituted-2-oxazoline)s 1 Mengshi Yang
- Poster Influence of Cu2+-doping in β-TCP on the hydration kinetics of brushite cement investigated by Rietveld analysis and heat flow calorimetry 1 Karla Späth
- Poster Analytical investigation of the influence of micro- and nanoplastic particles in crop plants by electron microscopic imaging and spectroscopy 1 Dr. Jörg Wissler
- Poster Influence of fluoride corrosion attack on the metal-porcelain bond strength of TiCr20 compared to titanium 1 Christine Schille
- Poster Bacterial nanocellulose loaded with frankincense extract as natural wound dressing to treat local dermal inflammations 1 Berit Karl
- Poster Graded functionalization of polydopamine coated fiber mats as potential implant for tendon-bone-transition 1 Sarah Oehmichen
- Poster Enhancing the functionalities of bioactive glass-based scaffolds by novel polymeric coatings 1 Dr. Liliana Liverani
- Poster Durability analysis of the cryopreservation of DNA origami nanostructures 1 Yang Xin
- Poster Effects of staple age on DNA origami nanostructure assembly and stability 1 Charlotte Kielar
- Poster Dual-setting brushite-silica gel cements – Variations of the monomer precursors and tuning of the setting parameters 1 Ib Holzmeister
- Poster Novel QCM-D/microscopy set-up for real-time analysis of bacterial binding onto biomaterial-coated sensors 1 Dr. Zeqian Xu
- Poster Chairside plasma activation of encapsulated implants: how fast is it? 1 Miguel Angel Garcia Chame
- Poster Nanostructured high-pressure laminate surfaces to reduce transmission pathways of pathogens in public transportation 1 Christian Helbing
- Poster Biomineralization of Recombinant Spider Silk Films 1 Vanessa J. Neubauer
- Poster Modification of bacterial cellulose to enhance anti-inflammatory wound dressing properties 1 Uwe Beekmann
- Poster Absolute Characterization of Synthetic Macromolecules used in Biomaterials Science Applications 1 Mandy Grube
- Poster Biodegradable thermoplastic materials for bimodal imaging containing the mineral present in the human body 1 Zaneta Górecka
- Poster Nano-rough titanium surfaces created by wet alkaline etching and PVD and their influence on bacterial adhesion as well as protein adsorption 1 Michaela Schürmann
- Poster Effective strategies for the controlling and dealing with transmission pathway of pathogens in air traffi 1 Christian Helbing
- Poster Cytotoxicity evaluation of biodegradable Zn-4Cu alloy using L929, Saos-2 and TAg cell lines 1 Ping Li
- Poster Influence of pulsed bias voltage on the tribological and morphological properties of a-C coatings deposited by an anodic arc method 1 Dipl.-Ing. Ingo Erdmann

Session P: Poster Session
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The brittleness of glass-ceramic scaffolds for bone tissue engineering can be overcome by the application of reinforcing mechanisms, such as coating with appropriate polymers for enhanced performance and function. The purpose of this study was the synthesis and characterization of biocompatible and biodegradable multiscale macro/mesoporous hybrid scaffolds, using new functionalized polyesters.

Bioactive glass-based scaffolds were fabricated by the foam replica technique and the selected composition for the bioactive glass was 1393. For establishing a mesoporous structure, a mesoporous magnesium-containing calcium silicate sol was synthesized by the sol-gel method. Droplets of the newly prepared sol were applied to the obtained bioactive glass scaffolds and after mild centrifuging for the removal of the excess sol, they were left to dry before their final sintering. The new biopolyester poly(glycerolsuccinate) (PGSu) was prepared by the reaction of trifunctional glycerol and diacid succinic acid in two steps: (a) prepolycondensation and (b) thermal crosslinking. Prepolymers with different properties were produced by changing parameters such as the molar concentration of the reactants, the COOH/OH ratio, and the reaction time/temperature. The solubility of the products was also tested using several common solvents. Solutions of PGSu were used to coat the bioactive glass-based scaffolds and another prepolymer, i.e. poly (glycerol sebacate) (PGS) was used as control. Suspensions containing the polymers (PGSu or PGS) and mesoporous magnesium-containing calcium silicate particles were used to obtain scaffolds with enhanced bioactivity. The morphology and porous structure of the scaffolds was investigated by SEM, their mechanical strength was evaluated under compressive stress and also their bioactivity was assessed. Positive and promising results in terms of enhancing the functionalities of bioactive glass-based scaffolds were reported for both tested polymers.

 

Speaker:
Dr. Liliana Liverani
Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU)
Additional Authors:
  • Evangelia Christodoulou
    Aristotle University of Thessaloniki
  • Dr. George S. Theodorou
    Aristotle University of Thessaloniki
  • Susanne Heid
    Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU)
  • Dimitra Patsiaoura
    Aristotle University of Thessaloniki
  • Prof. Dimitrios Bikiaris
    Aristotle University of Thessaloniki
  • Dr. Eleana Kontonasaki
    Aristotle University of Thessaloniki
  • Prof. Aldo R. Boccaccini
    Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU)