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Plenary Lecture

Biofabrication – Chances, Challenges and Limits

Thursday (09.05.2019)
08:00 - 08:30

08:00 - 08:30

Biofabrication is a young field of research that aims at the automated generation of hierarchical tissue-like structures from cells and materials through automated procedures in Bioprinting or Bioassembly [1]. This approach has the potential to overcome a number of classical challenges in relating to organization, personalized shape and mechanical integrity of generated constructs.
Although this has allowed achieving some remarkable early successes, it has recently become evident that the lack of variety in materials that can be formulated together with cells for Bioprinting, so called Bioinks [2], is one major drawback for the complete field [3]. Mainly, such materials are hydrogels or hydrogel precursor formulations; however, alternative approaches both regarding materials and printing techniques have recently been developed to extend this shortcoming. This contribution will give an introduction to the field, critically review the current status, including examples of our recent work, and also concern some of the current challenges.

[1] J. Groll, et al.: Biofabrication: Reappraising the definition of an evolving field. Biofabrication, 8, 013001 (2016)
[2] J. Groll, et al.: A Definition of Bioinks and their Distinction from Biomaterial Inks. Biofabrication, 11, 013001 (2019)
[3] T. Jüngst, et al.: Strategies and Molecular Design Criteria for 3D Printable Hydrogels. Chemical Reviews, 116 (3), 1496 (2016)

Prof. Dr. Jürgen Groll
University of Wuerzburg